May is Brain Cancer Awareness Month, let's bring the brain tumour community together to go grey, to raise awareness and funds for brain cancer research.
Our voices together can improve care and by raising awareness, our hope is to recognise the need for research and clinical studies to improve early diagnosis, standardise treatment, and improve the health of those children living with this disease.
Brain Cancer Awareness Month is made possible through collaboration with Cancer Australia, Love for Lachie, Run DIPG, Robert Connor Dawes Foundation, Australia New Zealand Children’s Haematology/Oncology Group, Children’s Hospital Foundation, Isabella and Marcus Foundation, and Brain Child Foundation.
At its completion, this project aims to produce the data required for a clinical trial of fenretinide combination therapy in DIPG.
The Wainwright lab discovered that a drug recently approved to treat women with late stage breast cancer, can be repurposed to great effect to treat medulloblastoma in children.
Evidence gathered from this study has strong potential to change the future clinical management of children with medulloblastoma.
The results of this project will lead directly to a rationally designed combination clinical trial that has the potential to directly impact on DIPG patients and improve their outcomes.
Using functional genomics and bioinformatics the Wainwright lab searched for potential new therapeutics for the disease and discovered CDK4/6 - a new drug – with a lot of potential.
This important discovery will be used to develop the optimal combination therapy at the bench with a view to fast tracking findings to the bedside to directly benefit children with DIPG.
This international collaborative clinical trial is the first of its kind for newly-diagnosed AYA medulloblastoma patients.
‘Printing’ brain tumours in gels as well as growing ‘mini-brains’ from human stem cells will help to more accurately measure the likely success of drugs for treating patients with brain cancer.
Less than 10% of children diagnosed with this deadly brain cancer survive beyond two years. Innovative treatment approaches are urgently needed.
Good Friday in 2019 did not live up to its name for mum Serina Peries as her baby daughter Amelia was diagnosed with a devestating brain cancer.