Sarcoma From bench to bedside – Developing an osteosarcoma precision oncology workflow Recipient: Dr Jacqui McGovern Institute: Queensland University of Technology Funding: $299,171 January 2022 to December 2024
Various types iBounce digital health educational program Recipient: Ms Lauren Ha Institute: Kids Cancer Centre, Sydney Children’s Hospital Randwick Funding: $299,905 January 2022 to December 2024
Brain cancer Pharmaco-phospho-proteo-genomics of paediatric high-grade glioma (HGG) Recipient: Associate Professor Matt Dun Institute: The University of Newcastle, Hunter Medical Research Institute Funding: $300,000 October 2021 to September 2024
DIPG Targeting the thioredoxin system as a novel strategy for DIPG Recipient: Associate Professor David Ziegler and Dr Dannielle Upton Institute: Children’s Cancer Institute Funding: $329,440 January 2022 to December 2024
Sarcoma INTER-EWING-1: Improving outcomes of newly diagnosed Ewing sarcoma Recipient: Associate Professor Geoff McCowage Institute: Children’s Hospital at Westmead Funding: $300,000 October 2021 to September 2024
Various types Reducing long-term side-effects of chemotherapy in cancer survivors Recipient: Professor Irina Vetter Institute: The University of Queensland Funding: $298,141 October 2021 to September 2024
Sarcoma Exploiting the DNA damage response in paediatric sarcoma Recipient: Dr Emmy Fleuren and Dr Emmy Dolman Institute: Children’s Cancer Institute Funding: $261,649 June 2021 to June 2024
Sarcoma Detecting chemotherapy resistance and sequencing residual malignant tissues in sarcoma treatment Recipient: Professor Glenn Marshall Institute: Children's Cancer Institute Funding: $220,000 January 2022 to December 2023
Leukaemia Targeting altered serine metabolism in MLL-rearranged paediatric acute myeloid leukaemia (AML) Recipient: Professor Ricky Johnstone Institute: Peter MacCallum Cancer Centre Funding: $218,338 October 2021 to September 2023
Brain cancer Enhancing radiation therapy to improve survival outcomes for children with aggressive brain cancer Recipient: Professor Nick Gottardo Institute: Telethon Kids Institute Funding: $108,556 October 2021 to September 2022
Sarcoma Identifying the right sarcoma treatment at the right time Recipient: Dr Emmy Fleuren Institute: Children’s Cancer Institute Funding: $186,799.50 June 2021 to June 2024
Various types National Tumour Biobanking Network Recipient: Associate Professor Andrew Moore Institute: University of Queensland Funding: $642,168 July 2015 to June 2024
Sarcoma Targeting IL-23 in bone and soft tissue sarcomas Recipient: Professor David Thomas Institute: Garvan Institute of Medical Research Funding: $100,000 March 2021 to March 2023
Neuroblastoma Enhanced polyamine depletion for aggressive childhood cancers Recipient: Professor Michelle Haber Institute: Children’s Cancer Institute TKCP funding: $239,995 January 2021 to December 2023 PdCCRS* funding: $347,705 Total funding: $587,700
Medulloblastoma Personalised targeted therapy for adolescent and young adult medulloblastoma patients Recipient: Dr Elizabeth Hovey Institute: Nelune Comprehensive Cancer Centre TKCP funding: $287,322 July 2020 to June 2023 PdCCRS* funding: $287,322 Total funding: $574,664
Brain cancer CONNECT-1903 Recipient: Professor Nick Gottardo Institute: ANZCHOG Funding: $54,095 June 2020 to December 2023
Medulloblastoma Application of gene-silencing nanodrugs to inhibit medulloblastoma growth Recipient: Associate Professor Joshua McCarroll Institute: Children’s Cancer Institute TKCP funding: $298,554 December 2019 to January 2023 PdCCRS* funding: $298,554 Total funding: $597,108
Various types Reboot-Kids Recipient: Dr Jennifer Cohen and Professor Claire Wakefield Institute: Sydney Children’s Hospital, Kids Cancer Centre Funding: $249,972 July 2019 to June 2023
Various types Pre-clinical anti CD-47 therapy Recipient: Dr Raelene Endersby and Professor Nick Gottardo Institute: Telethon Kids Institute Funding: $98,716 July 2021 to June 2022
DIPG Targeting Polo-like kinase 1 as a novel therapeutic opportunity for diffuse intrinsic pontine glioma Recipient: Associate Professor David Ziegler Institute: Sydney Children's Hospital TKCP funding: $278,282 July 2019 to June 2022 PdCCRS* funding: $278,282 Total funding: $556,563
Various types The NORTH Trial Recipient: Dr Paul Wood Institute: ANZCHOG Funding: $61,420 July 2018 to June 2022
Neuroblastoma “Cage fighting" with neuroblastoma Recipient: Dr Andrew Care Institute: Macquarie University The Kids’ Cancer Project funding: $63,926 May 2020 to April 2023 PdCCRS* funding: $127,854 Total funding: $191,780
Sarcoma Intraoperative immunotherapy to prevent relapse in soft tissue sarcoma Recipient: Dr W Joost Lesterhuis Institute: Telethon Kids Institute TKCP funding: $197,525 April 2020 to March 2022 PdCCRS* funding: $395,050 Total funding: $197,525
Medulloblastoma Using smarter new drugs to reduce long term debilitating side effects for aggressive childhood brain Recipient: Professor Nick Gottardo and Dr Raelene Endersby Institute: Telethon Kids Institute Funding: $246,713 July 2020 to June 2021
Various types International clinical trials support Recipient: Australian and New Zealand Children’s Haematology/Oncology Group Funding: $1,075,000 July 2015 to June 2023
Various types Personalised Medicine: Zero Childhood Cancer Recipient: Professor Michelle Haber Institute: Children’s Cancer Institute Funding: $2,287,250 July 2014 to September 2023
Medulloblastoma Exploiting CDK4/6 inhibition to treat medulloblastoma Recipient: Professor Brandon Wainwright Institute: University of Queensland TKCP funding: $196,207 July 2019 to June 2022 PdCCRS* funding: $392,413 Total funding: $588,620
Leukaemia Targeting the NAD pathway as a new therapeutic strategy for high-risk leukaemia in children Recipient: Dr Michelle Henderson Institute: University of NSW TKCP funding: $138,179 July 2019 to June 2022 PdCCRS* funding: $453,279 Total funding: $591,458
Leukaemia IntReALL-HR Recipient: Associate Professor Tamas Revesz Institute: Women's and Children's Hospital, Adelaide Funding: $416,422 July 2018 to June 2022
Various types Understanding the genetic basis of chemotherapy-induced cardiomyopathy Recipient: Dr Rachel Conyers Institute: The Murdoch Children’s Research Institute Funding: $583,072 July 2018 to December 2022
Various types New state-wide Children’s and Adolescent/Young Adult Cancer Clinical Trials Unit Recipient: Associate Professor John Heath Institute: Royal Hobart Hospital Funding: $308,517 July 2017 to December 2022
Leukaemia Pre-clinical development of novel immune therapy for paediatric cancers Recipient: Dr Alla Dolnikov Institute: Sydney Children's Hospital, Randwick Funding: $480,000 July 2016 to December 2022
Leukaemia Investigating drug resistance and genetic changes in Ph-like ALL in adolescents Recipient: Dr Susan Heatley Institute: South Australian Health & Medical Research Institute Funding: $398,146 July 2016 to June 2022
DIPG Epigenetic targeted therapy in DIPG Recipient: Associate Professor David Ziegler Institute: Children’s Cancer Institute Funding: $251,428 July 2019 to May 2022
Various types Impact of treatment on late effects and survivorship on childhood cancer survivors Recipient: Professor Natasha Nassar Institute: University of Sydney Funding: $39,578 July 2019 to December 2021
Various types Developing treatments for vincristine-induced neuropathy Recipient: Associate Professor Irina Vetter Institute: The University of Queensland Funding: $255,978 July 2019 to August 2021
Testicular Development of a non-invasive diagnostic and prognostic assay for adolescent testicular cancer Recipient: Dr Cassy Spiller Institute: The University of Queensland Funding: $50,000 July 2019 to December 2021
Neuroblastoma MicroRNA drugs for the treatment of neuroblastoma Recipient: Associate Professor Alexander Swarbrick Institute: Garvan Institute of Medical Research Funding: $308,270 July 2018 to September 2021
Various types 3D printers and mini-brains Recipient: Associate Professor Geraldine O’Neill Institute: The Children’s Hospital at Westmead Funding: $119,821 July 2019 to June 2020
Leukaemia Overcoming therapeutic resistance in high risk ALL using novel BH3 mimetic Recipient: Dr Diane Hanna Institute:The Walter and Eliza Hall Institute Funding: $100,000 July 2019 to September 2020
Medulloblastoma Using targeted chemotherapies to reduce intensity of radiotherapy in medulloblastoma Recipient: Dr Nick Gottardo Institute: Telethon Kids Institute Funding: $256,342 July 2018 to June 2020
Various types New therapies for incurable paediatric brain tumours Recipient: Professor Brandon Wainwright Institute: The Institute of Molecular Bioscience Funding: $224,936 July 2018 to June 2020
Leukaemia Combinational therapeutics in high-risk infant acute lymphoblastic leukaemia Recipient: Dr Rishi Kotecha Institute: Telethon Kids Institute Funding: $445,695 July 2017 to June 2020
Leukaemia Reversing glucocorticoid resistance in paediatric acute lymphoblastic leukaemia – a novel epigenetic Recipient: Professor Richard Lock Institute: Children’s Cancer Institute Funding: $103,571 July 2017 to June 2020
Various types Ready, Steady, School Recipient: Dr Joanna Fardell Institute: UNSW Australia Funding: $523,308 July 2016 to December 2020
Neuroblastoma Targeting FACT to inhibit MYCN-driven transcription in neuroblastoma Recipient: Dr Daniel Carter Institute: UNSW Australia Funding: $296,428 July 2016 to June 2020
Sarcoma Exploring better and safer treatments for osteosarcoma Recipient: Associate Professor Christine Hawkins Institute: La Trobe University Funding: $382,713 July 2016 to June 2020
Leukaemia Therapeutic targeting transcriptional addiction in paediatric leukaemias Recipient: Professor Ricky Johnstone Institute: Peter MacCallum Cancer Centre Funding: $496,282 July 2016 to June 2020
DIPG Synthetic retinoid therapy for diffuse intrinsic pontine glioma Recipient: Associate Professor David Ziegler Institute: Children’s Cancer Institute Funding: $200,000 July 2016 to December 2020
Various types Development of CAR T cell immunotherapies for paediatric patients Recipient: Dr Belinda Kramer and Dr Geoff McCowage Institute: The Children’s Hospital at Westmead Funding: $4,309,610 July 2010 to June 2020
Medulloblastoma Development of personalised medicine approaches to treat medulloblastoma Recipient: Professor Bryan Day Institute: QIMR Berghofer Medical Research Institute Funding: $263,960 July 2016 to June 2019
DIPG Novel therapies for diffuse intrinsic pontine glioma (DIPG) Recipient: Associate Professor David Ziegler Institute: Children’s Cancer Institute Funding: $583,142 July 2016 to June 2019
Medulloblastoma Improving chemotherapy regimens for medulloblastoma Recipient: Dr Nick Gottardo Institute: Telethon Kids Institute Funding: $252,987 July 2016 to June 2018
Various types Next gen sequencing to identify gene mutations in childhood cancer patients Recipient: Professor Jennifer Byrne and Dr Luciano Dalla-Pozza Institute: The Children's Hospital at Westmead Funding: $75,000 July 2017 to June 2018
Medulloblastoma New therapeutic targets for paediatric medulloblastoma Recipient: Dr Bryan Day Institute: QIMR Berghofer Medical Research Institute Funding: $208,549 July 2014 to June 2015 and July 2017 to June 2018
Medulloblastoma Novel targets to treat medulloblastoma Recipient: Professor Brandon Wainwright Institute: Institute for Molecular Bioscience Funding: $260,420 July 2016 to June 2018
Leukaemia Personalised disease monitoring in childhood AML Recipient: Dr Andrew Moore Institute: University of Queensland Diamantina Institute Funding: $474,591 July 2014 to June 2019
Various types Re-engage Recipient: Professor Claire Wakefield Institute: UNSW Australia Funding: $300,381 July 2015 to June 2018
Leukaemia Improving treatments for infant acute lymphoblastic leukaemia (iALL) Recipient: Professor Ursula Kees and Dr Rishi Kotecha Institute: Telethon Kids Institute Funding: $475,217 July 2014 to June 2018
Neuroblastoma International DFMO clinical trial Recipient: Associate Professor David Ziegler Institute: Children’s Cancer Institute Funding: $448,142 June 2014 to July 2018
Various types Drug discovery project Recipient: Professor Peter Gunning Institute: UNSW Australia Funding: $5,884,000 July 2010 to June 2018
Various types Treatment of solid paediatric cancers with tropomyosin targeted therapy Recipient: Professor Timothy Cripe Institute: Nationwide Children’s Hospital, Ohio Funding: $600,000 July 2011 to June 2018
Various types Tumour Bank at CHW Recipient: Associate Professor Daniel Catchpoole Institute: The Children’s Hospital at Westmead Funding: $2,425,000 July 2010 to June 2018
Various types Developing novel immunotherapies for childhood blood cancers Recipient: Dr Andrew Moore Institute: University of Queensland Diamantina Institute Funding: $ 87,000 from July 2016 to June 2017
Neuroblastoma Stathmin regulation of microRNA expression in neuroblastoma cells Recipient: Professor Maria Kavallaris Institute: Children’s Cancer Institute Funding: $820,173 July 2009 to June 2017
Various types Bio-banking and personalised medicine software platform Recipient:Professor Glenn Marshall Institute: Kids Cancer Alliance Funding: $240,000 July 2015 to June 2016
Medulloblastoma Improving the cure rates of childhood brain cancer Recipient: Dr Nick Gottardo Institute: Telethon Kids Institute Funding: $64,562 July 2015 to June 2016
Neuroblastoma Switching off genes Recipient: Dr Alex Swarbrick Institute: Garvin Institute of Medical Research Funding: $385,000 July 2012 to June 2016
Neuroblastoma Clinical trial of new treatment for relapsed neuroblastoma Recipient: Professor Michelle Haber Institute: Children's Cancer Institute Funding: $300,000 July 2013 to June 2016
Various types Evaluating potential side effects of anti-tropomyosins Recipient: Professor Edna Hardeman Institute: University of NSW Funding: $550,000 July 2011 to June 2016
Neuroblastoma Cytoskeletal regulation of adhesion dynamics in neuroblastoma metastases Recipient: Associate Professor Geraldine O'Neill Institute: The Children's Hospital at Westmead Funding: $500,000 July 2010 to June 2016
Neuroblastoma Role of microRNAs in neuroblastoma Recipient: : Associate Professor Gregory Goodall and Dr Yeesim Khew-Goodall Institute: Centre for Cancer Biology Funding: $550,000 July 2010 to June 2016
Neuroblastoma Understanding neuroblastoma cell migration Recipient: Professor Alpha Yap Institute: Institute for Molecular Bioscience Funding: $623,000 July 2009 to June 2016
Various types Determine how disruption of Tm5NM1 leads to programed cell death Recipient: Professor Peter Gunning Institute: University of NSW Funding: $450,000 July 2010 to June 2015
Neuroblastoma Muscle stem cell Recipient: Professor Peter Gunning Institute: University of NSW Funding: $300,000 July 2010 to June 2014
Various types Modelling paediatric brain tumours in Drosophila Recipient: Associate Professor Helena Richardson Institute: Peter MacCallum Cancer Centre Funding: $400,000 July 2009 to June 2014
Various types Improving treatments for adolescents and young adults Recipient: Dr Michael Coory Institute: Murdoch Children’s Research Institute Funding: $50,000 July 2012 to June 2013
Neuroblastoma Neuroblastoma sensitivity to chemotherapy Recipient: Dr Ora Bernard Institute: St Vincent's Institute Funding: $300,000 July 2009 to June 2013
Various types Translational research at the Biospecimens Research Group and Tumour Bank Recipient: Dr Daniel Catchpoole Institute: The Children's Hospital at Westmead Funding: $50,000 July 2010 to June 2011