Can cord blood prevent relapse in childhood Leukaemia.
For children who have relapsed from leukaemia, therapeutic options are currently limited. This project proposes to utilise the therapeutic potential of Natural Killer (NK) cells, a type of immune cells able to kill leukaemia cancer cells.
Using state-of-the-art preclinical models, Dr Guillerey plans to develop a new method to expand NK cells from cord blood and test their ability to protect against paediatric leukaemia. Our research will provide critical data to inform the design of NK cell-based immunotherapies.
This project will generate pivotal pre-clinical data to develop new immunotherapies for young cancer patients. Although this project has a focus on childhood leukaemia, immunotherapeutic approaches developed in this proposal could also be applied to other cancers.
Dr Camille Guillerey
University of Queensland
The Kids’ Cancer Project funding $49,685.50 (February 2022 to February 2024)
Cancer Australia PdCCRS funding $149,056.50
Paediatric high-grade glioma (HGG)
This project focuses on improving treatment and survival for children with some of the most high-risk brain cancers
Providing access to international clinical trials and additional clinical trial expertise.
ANZCHOG international trials set up initiation and national trial management.
RECOVER – Responding to late effects in survivors of childhood cancer
Empowering young survivors of childhood cancer to transition to adulthood with the knowledge, skills and resources required to manage their ongoing health needs.
Survive Blood Cancer
Utilising cord blood-derived Natural Killer cells to prevent post-transplant relapse in Childhood Leukaemia.
Treatment toxicity can cause infertility
Developing genetic risk prediction of long term infertility from childhood cancer therapies leading to informed decisions and application of preventive measures.
Bone & Soft Tissue Cancer | Sarcoma
Clinical translation of laboratory tested CAR T cell therapy into Phase 1 trials for paediatric treatment of sarcoma.
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