Brain tumours are the most common solid tumours in children. They can be difficult to treat because often the cancer grows among healthy brain tissue, meaning it can’t be removed without damaging vital functions like breathing, swallowing and movement.
Unfortunately, the level of chemotherapy
needed to treat a child's brain tumour can also cause significant side effects in the bone marrow
and immune system
The trial, funded by The Kids’ Cancer Project and conducted by Dr Geoff McCowage and Dr Belinda Kramer at The Children’s Hospital at Westmead, is a Phase I
trial: it tests the safety and feasibility of altering a child's bone marrow to make it resistant to chemotherapy.